DCK Antikörper

Produktnummer ABIN2855484

Produktdetails anti-DCK Antikörper

Target: DCK (Deoxycytidine Kinase (DCK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to DCK (deoxycytidine kinase)
DCK antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human DCK. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: PC-12 , Rat2 , A549 , H1299 , 293T , DCK-transfected 293T

Validation: KO/KD, Overexpression

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.41 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu DCK

Target: DCK (Deoxycytidine Kinase (DCK))

Andere Bezeichnung: deoxycytidine kinase (DCK Produkte)

Synonyme: dck antikoerper, DCK antikoerper, wu:fc15f06 antikoerper, zgc:101771 antikoerper, dck1 antikoerper, deoxycytidine kinase antikoerper, deoxycytidine kinase, gene 2 L homeolog antikoerper, deoxycytidine kinase, gene 2 antikoerper, Deoxycytidine kinase antikoerper, deoxycytidine kinase, gene 1 L homeolog antikoerper, DCK antikoerper, dck antikoerper, dck.2.L antikoerper, dck.2 antikoerper, Dck antikoerper, FPV059 antikoerper, FPV151 antikoerper, dck.1.L antikoerper

Hintergrund: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

Cellular Localization: Nucleus

Molekulargewicht: 31 kDa

Gen-ID: 1633

UniProt: P27707