DIAPH3 Antikörper (Center)

Produktnummer ABIN2855508

Produktdetails anti-DIAPH3 Antikörper

Target: DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DIAPH3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Rind (Kuh)

Kreuzreaktivität (Details): Bovine (90 %)

Produktmerkmale: Rabbit polyclonal antibody to DIAPH3 (diaphanous homolog 3 (Drosophila))
DIAPH3 antibody [C1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DIAPH3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*

Kommentare:

Positive Control: Target recombinant protein

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu DIAPH3

Target: DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

Andere Bezeichnung: DIAPH3 (DIAPH3 Produkte)

Hintergrund: Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics.

Molekulargewicht: 137 kDa

Gen-ID: 81624