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SP1 Antikörper (C-Term)

Name: SP1 Antikörper (C-Term)
Brand: antibodies-online
SKU: ABIN2855540
Price: 659.23 EUR
Availability: InStock

SP1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

WB Image SP1 antibody detects SP1 protein by western blot analysis. (SP1 Antikörper (C-Term))

IHC-P Image SP1 antibody detects SP1 protein at nucleus on human gastric carcinoma by immunohistochemical analysis. (SP1 Antikörper (C-Term))

IHC

IHC-P Image SP1 antibody detects SP1 protein at nucleus on human ovarian carcinoma by immunohistochemical analysis. (SP1 Antikörper (C-Term))

IHC

ICC/IF Image SP1 antibody detects SP1 protein at nucleus by immunofluorescent analysis. (SP1 Antikörper (C-Term))

WB Image Sample (30 ug of whole cell lysate) A: THP-1 5% SDS PAGE antibody diluted at 1:1000 (SP1 Antikörper (C-Term))

6 Abbildungen

Produktnummer ABIN2855540

Datenblatt (PDF)

Target Alle SP1 Antikörper anzeigen

SP1 (Sp1 Transcription Factor (SP1))
Bindungsspezifität
21

12

10

7

4

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reaktivität
87

60

39

11

8

7

6

5

5

5

4

2

2

2

1
Human
Wirt
89

13

3
Kaninchen
Passende Sekundärantikörper
Klonalität
83

22
Polyklonal
Konjugat
71

4

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser SP1 Antikörper ist unkonjugiert
Applikation
90

45

45

36

21

15

14

13

12

8

4

3

3

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität

Human

Produktmerkmale

Rabbit Polyclonal antibody to SP1 (Sp1 transcription factor)
SP1 antibody

Aufreinigung

Purified by antigen-affinity chromatography.

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human SP1. The exact sequence is proprietary.

Isotyp

IgG

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anti-Sp1 Transcription Factor (SP1) (AA 677-707) antibody
SP1 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare

Positive Control: THP-1

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel

Thimerosal (Merthiolate)

Vorsichtsmaßnahmen

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target

SP1 (Sp1 Transcription Factor (SP1))

Andere Bezeichnung

Sp1 transcription factor (SP1 Produkte)

Hintergrund

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

Cellular Localization: Nucleus

Molekulargewicht

81 kDa

Gen-ID

6667

UniProt

P08047

Pathways

Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction