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SP1 Antikörper (C-Term)

Name: SP1 Antikörper (C-Term)
Brand: antibodies-online
SKU: ABIN2855540
Price: 630.63 EUR
Availability: InStock

SP1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

WB Image SP1 antibody detects SP1 protein by western blot analysis. (SP1 Antikörper (C-Term))

IHC-P Image SP1 antibody detects SP1 protein at nucleus on human gastric carcinoma by immunohistochemical analysis. (SP1 Antikörper (C-Term))

IHC

IHC-P Image SP1 antibody detects SP1 protein at nucleus on human ovarian carcinoma by immunohistochemical analysis. (SP1 Antikörper (C-Term))

IHC

ICC/IF Image SP1 antibody detects SP1 protein at nucleus by immunofluorescent analysis. (SP1 Antikörper (C-Term))

WB Image Sample (30 ug of whole cell lysate) A: THP-1 5% SDS PAGE antibody diluted at 1:1000 (SP1 Antikörper (C-Term))

6 Abbildungen

Produktnummer ABIN2855540

Datenblatt (PDF)

Target Alle SP1 Antikörper anzeigen

SP1 (Sp1 Transcription Factor (SP1))
Bindungsspezifität
21

14

12

7

7

7

6

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reaktivität
97

67

46

11

8

7

6

5

5

5

4

2

2

2

1
Human
Wirt
99

13

3
Kaninchen
Passende Sekundärantikörper
Klonalität
94

21
Polyklonal
Konjugat
70

6

3

3

3

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser SP1 Antikörper ist unkonjugiert
Applikation
93

49

47

40

20

15

14

14

13

7

3

3

3

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität

Human

Produktmerkmale

Rabbit Polyclonal antibody to SP1 (Sp1 transcription factor)
SP1 antibody

Aufreinigung

Purified by antigen-affinity chromatography.

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human SP1. The exact sequence is proprietary.

Isotyp

IgG

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SP1 Reaktivität: Human, Maus WB, ELISA, IF Wirt: Maus Monoclonal 4H6 unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 677-707) antibody
SP1 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare

Positive Control: THP-1

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel

Thimerosal (Merthiolate)

Vorsichtsmaßnahmen

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target

SP1 (Sp1 Transcription Factor (SP1))

Andere Bezeichnung

Sp1 transcription factor (SP1 Produkte)

Synonyme

fc18h09 antikoerper, zgc:85950 antikoerper, wu:fc18h09 antikoerper, SP1 antikoerper, 1110003E12Rik antikoerper, AA450830 antikoerper, AI845540 antikoerper, Sp1-1 antikoerper, sp1 transcription factor antikoerper, Sp1 transcription factor antikoerper, Sp1 transcription factor L homeolog antikoerper, trans-acting transcription factor 1 antikoerper, sp1 antikoerper, SP1 antikoerper, Sp1 antikoerper, sp1.L antikoerper

Hintergrund

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

Cellular Localization: Nucleus

Molekulargewicht

81 kDa

Gen-ID

6667

UniProt

P08047

Pathways

Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction