STIP1 Antikörper

Produktnummer ABIN2855549

Produktdetails anti-STIP1 Antikörper

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to STIP1 (stress-induced-phosphoprotein 1)
STIP1 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human STIP1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , HepG2 , Molt-4

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu STIP1

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Andere Bezeichnung: stress induced phosphoprotein 1 (STIP1 Produkte)

Synonyme: HOP antikoerper, IEF-SSP-3521 antikoerper, P60 antikoerper, STI1 antikoerper, STI1L antikoerper, Hop antikoerper, Sti1 antikoerper, p60 antikoerper, MGC53256 antikoerper, stip1 antikoerper, MGC76181 antikoerper, MGC82554 antikoerper, zgc:92133 antikoerper, stress induced phosphoprotein 1 antikoerper, stress-induced phosphoprotein 1 antikoerper, stress induced phosphoprotein 1 L homeolog antikoerper, Stress-induced-phosphoprotein 1 antikoerper, stress-induced-phosphoprotein 1 antikoerper, stress induced phosphoprotein 1 S homeolog antikoerper, STIP1 antikoerper, Stip1 antikoerper, stip1.L antikoerper, GL50803_27310 antikoerper, PGTG_06468 antikoerper, stip1 antikoerper, stip1.S antikoerper

Hintergrund: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A, MIM 140550) and HSP90 (see HSP90AA1, MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM]

Cellular Localization: Cytoplasm (By similarity) , Nucleus

Molekulargewicht: 63 kDa

Gen-ID: 10963

UniProt: P31948