XPA Antikörper (Center)

Produktnummer ABIN2855566

Produktdetails anti-XPA Antikörper

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Produktmerkmale: Rabbit Polyclonal antibody to XPA (xeroderma pigmentosum, complementation group A)
XPA antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human XPA. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:500-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:500-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: A549

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-XPA Antikörper (ABIN2855566)

Manandhar, Lowery, Boulware, Lin, Lu, Wood: "Transcriptional consequences of XPA disruption in human cell lines." in: DNA repair, Vol. 57, pp. 76-90, (2017) (PubMed).

Details zu XPA

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Andere Bezeichnung: XPA (XPA Produkte)

Synonyme: CG6358 antikoerper, DhR14 antikoerper, DhXPA antikoerper, DmXPA antikoerper, Dmel\\CG6358 antikoerper, Dxpa antikoerper, EG:EG0007.8 antikoerper, XPAC antikoerper, XPA_DROME antikoerper, Xpa antikoerper, dmXPA antikoerper, dxpa antikoerper, XP1 antikoerper, AI573865 antikoerper, Xpac antikoerper, xpac antikoerper, xxpa antikoerper, Xeroderma pigmentosum group A-like antikoerper, XPA, DNA damage recognition and repair factor antikoerper, xeroderma pigmentosum, complementation group A antikoerper, xeroderma pigmentosum, complementation group A L homeolog antikoerper, Xpac antikoerper, XPA antikoerper, Xpa antikoerper, xpa.L antikoerper

Hintergrund: This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.

Cellular Localization: Nucleus

Molekulargewicht: 31 kDa

Gen-ID: 7507

Pathways: DNA Reparatur