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Nibrin Antikörper

KO Validated NBN Reaktivität: Human WB, IF, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855584
  • Target Alle Nibrin (NBN) Antikörper anzeigen
    Nibrin (NBN)
    Reaktivität
    • 100
    • 60
    • 36
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 117
    • 15
    Kaninchen
    Klonalität
    • 108
    • 24
    Polyklonal
    Konjugat
    • 66
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Nibrin Antikörper ist unkonjugiert
    Applikation
    • 103
    • 47
    • 27
    • 27
    • 26
    • 26
    • 23
    • 17
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit Polyclonal antibody to NBS1 (nibrin)
    NBS1 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human NBS1. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product NBN Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: NT2D1 , 293T , A431 , HeLa , HepG2 , 293T

    Validation: KO/KD

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Nibrin (NBN)
    Andere Bezeichnung
    nibrin (NBN Produkte)
    Synonyme
    NBN antikoerper, AT-V1 antikoerper, AT-V2 antikoerper, ATV antikoerper, NBS antikoerper, NBS1 antikoerper, P95 antikoerper, Nbs1 antikoerper, im:6911679 antikoerper, zgc:194152 antikoerper, nibrin antikoerper, NBN antikoerper, nbn antikoerper, Nbn antikoerper
    Hintergrund
    Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

    Cellular Localization: Nucleus (By similarity) , Telomere (By similarity)
    Molekulargewicht
    85 kDa
    Gen-ID
    4683
    UniProt
    O60934
    Pathways
    DNA Reparatur, Production of Molecular Mediator of Immune Response
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