Osteoactivin Antikörper
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- Target Alle Osteoactivin (GPNMB) Antikörper anzeigen
- Osteoactivin (GPNMB)
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Osteoactivin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human
- Produktmerkmale
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Rabbit Polyclonal antibody to GPNMB (glycoprotein (transmembrane) nmb)
GPNMB antibody [N2C2], Internal - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human GPNMB. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product GPNMB Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: SKBR3
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Osteoactivin (GPNMB)
- Andere Bezeichnung
- glycoprotein nmb (GPNMB Produkte)
- Synonyme
- HGFIN antikoerper, NMB antikoerper, DC-HIL antikoerper, Dchil antikoerper, ipd antikoerper, glycoprotein nmb antikoerper, glycoprotein (transmembrane) nmb antikoerper, glycoprotein nmb L homeolog antikoerper, Gpnmb antikoerper, GPNMB antikoerper, gpnmb.L antikoerper
- Hintergrund
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The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Membrane, Single-pass type I membrane protein (Potential) , Melanosome - Molekulargewicht
- 64 kDa
- Gen-ID
- 10457
- UniProt
- Q14956
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