ACTR2 Antikörper

Produktnummer ABIN2855610

Produktdetails anti-ACTR2 Antikörper

Target: ACTR2 (Actin-Related Protein 2 (ACTR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACTR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Drosophila melanogaster, Human, Maus, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to Arp2 (ARP2 actin-related protein 2 homolog (yeast))
Arp2 antibody [N1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Arp2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: H1299

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.41 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-ACTR2 Antikörper (ABIN2855610)

Graziano, Town, Sitarska, Nagy, Fošnarič, Penič, Iglič, Kralj-Iglič, Gov, Diz-Muñoz, Weiner: "Cell confinement reveals a branched-actin independent circuit for neutrophil polarity." in: PLoS biology, Vol. 17, Issue 10, pp. e3000457, (2020) (PubMed).

Details zu ACTR2

Target: ACTR2 (Actin-Related Protein 2 (ACTR2))

Andere Bezeichnung: actin related protein 2 (ACTR2 Produkte)

Hintergrund: The specific function of this gene has not yet been determined, however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Cytoplasm , cytoskeleton , Cell projection

Molekulargewicht: 45 kDa

Gen-ID: 10097

UniProt: P61160

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization