Plastin 3 Antikörper

Produktnummer ABIN2855613

Produktdetails anti-Plastin 3 Antikörper

Target: Plastin 3 (PLS3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Plastin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to T-Plastin (plastin-3)
T-Plastin antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human T-Plastin. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: NIH-3T3 , JC , BCL-1 , 293T , A431 , Jurkat , Raji

Validation: KO/KD, Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.23 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu Plastin 3

Target: Plastin 3 (PLS3)

Andere Bezeichnung: plastin 3 (PLS3 Produkte)

Synonyme: T-plastin antikoerper, AI115446 antikoerper, AL024105 antikoerper, T-fimbrin antikoerper, MGC68681 antikoerper, t-plastin antikoerper, MGC106020 antikoerper, DKFZp459D0939 antikoerper, PLS3 antikoerper, Plastin-3 antikoerper, wu:fc04g03 antikoerper, zgc:91903 antikoerper, plastin 3 antikoerper, plastin 3 (T-isoform) antikoerper, plastin 3 L homeolog antikoerper, plastin 3 (T isoform) antikoerper, PLS3 antikoerper, Pls3 antikoerper, pls3.L antikoerper, pls3 antikoerper

Hintergrund: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83 % identical. It contains a potential calcium-binding site near the N terminus. Two transcript variants encoding the same protein have been found for this gene.

Cellular Localization: Cytoplasm

Molekulargewicht: 71 kDa

Gen-ID: 5358

UniProt: P13797