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Kallikrein 7 Antikörper

KLK7 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855653
  • Target Alle Kallikrein 7 (KLK7) Antikörper anzeigen
    Kallikrein 7 (KLK7)
    Reaktivität
    • 43
    • 30
    • 18
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 71
    • 6
    Kaninchen
    Klonalität
    • 74
    • 3
    Polyklonal
    Konjugat
    • 28
    • 13
    • 11
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Kallikrein 7 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 30
    • 25
    • 13
    • 13
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit Polyclonal antibody to KLK7 (kallikrein-related peptidase 7)
    KLK7 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Kallikrein 7. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product KLK7 Primärantikörper
  • Applikationshinweise
    WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Kallikrein 7-transfected 293T

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.69 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Delaunay, Deschamps, Haddada, Walker, Soosaipillai, Soualmia, El Amri, Diamandis, Brattsand, Magdolen, Darmoul: "Aberrant expression of kallikrein-related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasion." in: Molecular oncology, Vol. 11, Issue 10, pp. 1330-1347, (2018) (PubMed).

  • Target
    Kallikrein 7 (KLK7)
    Andere Bezeichnung
    kallikrein related peptidase 7 (KLK7 Produkte)
    Synonyme
    Prss6 antikoerper, SCCE antikoerper, PRSS6 antikoerper, hK7 antikoerper, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) antikoerper, kallikrein-related peptidase 7 antikoerper, kallikrein related peptidase 7 antikoerper, Klk7 antikoerper, KLK7 antikoerper
    Hintergrund
    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.

    Cellular Localization: Secreted
    Molekulargewicht
    28 kDa
    Gen-ID
    5650
    UniProt
    P49862
    Pathways
    Komplementsystem
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