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AKR1C4 Antikörper

AKR1C4 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855666
  • Target Alle AKR1C4 Antikörper anzeigen
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Reaktivität
    • 35
    • 9
    • 3
    Human
    Wirt
    • 28
    • 5
    • 1
    • 1
    Kaninchen
    Klonalität
    • 33
    • 2
    Polyklonal
    Konjugat
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AKR1C4 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 19
    • 7
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit polyclonal antibody to HSD3a (aldo-keto reductase family 1, member C4 (chlordecone reductase, 3-alpha hydroxysteroid dehydrogenase, type I, dihydrodiol dehydrogenase 4))
    HSD3a antibody [N1C2]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human HSD3a. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product AKR1C4 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: HeLa

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.83 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Andere Bezeichnung
    aldo-keto reductase family 1 member C4 (AKR1C4 Produkte)
    Synonyme
    3-alpha-HSD antikoerper, C11 antikoerper, CDR antikoerper, CHDR antikoerper, DD-4 antikoerper, DD4 antikoerper, HAKRA antikoerper, aldo-keto reductase family 1 member C4 antikoerper, AKR1C4 antikoerper
    Hintergrund
    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

    Cellular Localization: Cytoplasm
    Molekulargewicht
    37 kDa
    Gen-ID
    1109
    UniProt
    P17516
    Pathways
    Steroid Hormone Biosynthesis
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