Seladin 1 Antikörper
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- Target Alle Seladin 1 (DHCR24) Antikörper anzeigen
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Seladin 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
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Rabbit Polyclonal antibody to Seladin 1 (24-dehydrocholesterol reductase)
Seladin 1 antibody [N1C2] - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Seladin 1. The exact sequence is proprietary.
- Isotyp
- IgG
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anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 227-516) antibody
DHCR24 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 57-87), (N-Term) antibodyDHCR24 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB17628 unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 1-516) antibodyDHCR24 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 1-516) antibodyDHCR24 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (N-Term) antibodyDHCR24 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) antibodyDHCR24 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 218-246) antibodyDHCR24 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB17629 unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 38-87) antibodyDHCR24 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 431-480) antibodyDHCR24 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Affe, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (N-Term) antibodyDHCR24 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.47 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
- Andere Bezeichnung
- 24-dehydrocholesterol reductase (DHCR24 Produkte)
- Hintergrund
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This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Cellular Localization: Endoplasmic reticulum membrane , Golgi apparatus membrane - Molekulargewicht
- 60 kDa
- Gen-ID
- 1718
- UniProt
- Q15392
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