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FGFRL1 Antikörper

FGFRL1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855700
  • Target Alle FGFRL1 Antikörper anzeigen
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    Reaktivität
    • 51
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 52
    • 1
    • 1
    Kaninchen
    Klonalität
    • 52
    • 2
    Polyklonal
    Konjugat
    • 19
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FGFRL1 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 22
    • 21
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit polyclonal antibody to FGFR-5 (fibroblast growth factor receptor-like 1)
    FGFR-5 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human FGFR5. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product FGFRL1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: FGFRL1-transfected 293T , HepG2 membrane extract

    Validation: Orthogonal, Overexpression

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2.42 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    Andere Bezeichnung
    fibroblast growth factor receptor like 1 (FGFRL1 Produkte)
    Synonyme
    fgfrl1 antikoerper, zgc:64084 antikoerper, FGFR5 antikoerper, FGFR5beta antikoerper, FGFR5gamma antikoerper, Fgfr5 antikoerper, FHFR antikoerper, XFGFRL1 antikoerper, Xndk antikoerper, fgfrl1-a antikoerper, fgfrl1-b antikoerper, ndk antikoerper, im:7154242 antikoerper, fibroblast growth factor receptor like 1a antikoerper, fibroblast growth factor receptor-like 1 antikoerper, fibroblast growth factor receptor like 1 antikoerper, fibroblast growth factor receptor like 1 L homeolog antikoerper, fibroblast growth factor receptor like 1b antikoerper, fgfrl1a antikoerper, Fgfrl1 antikoerper, FGFRL1 antikoerper, fgfrl1.L antikoerper, fgfrl1b antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    Molekulargewicht
    55 kDa
    Gen-ID
    53834
    UniProt
    Q8N441
    Pathways
    RTK Signalweg
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