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IP6K1 Antikörper

KO Validated IP6K1 Reaktivität: Human WB, IP, ICC, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855731
  • Target Alle IP6K1 Antikörper anzeigen
    IP6K1 (Inositol Hexakisphosphate Kinase 1 (IP6K1))
    Reaktivität
    • 29
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 25
    • 4
    Kaninchen
    Klonalität
    • 28
    • 1
    Polyklonal
    Konjugat
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    Dieser IP6K1 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 15
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Spezifität
    Knockdown/Knockout validation was supported by references (PMID:27701146)
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit Polyclonal antibody to IP6K1 (inositol hexakisphosphate kinase 1)
    IP6K1 antibody
    Aufreinigung
    Affinity purified by Protein A.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human IP6K1. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Jurkat , Raji , NCI-H929

    Validation: KO/KD, Overexpression

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.22 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Zhu, Ghoshal, Tyagi, Chakraborty: "Global IP6K1 deletion enhances temperature modulated energy expenditure which reduces carbohydrate and fat induced weight gain." in: Molecular metabolism, Vol. 6, Issue 1, pp. 73-85, (2018) (PubMed).

  • Target
    IP6K1 (Inositol Hexakisphosphate Kinase 1 (IP6K1))
    Andere Bezeichnung
    inositol hexakisphosphate kinase 1 (IP6K1 Produkte)
    Hintergrund
    This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing occurs for this gene, however, the full-length nature of all transcript variants has not yet been described.

    Cellular Localization: Cytoplasm , Nucleus
    Molekulargewicht
    50 kDa
    Gen-ID
    9807
    UniProt
    Q92551
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