CD55 Antikörper (Center)

Produktnummer ABIN2855732

Produktdetails anti-CD55 Antikörper

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD55 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktmerkmale: Rabbit Polyclonal antibody to CD55 (CD55 Molecule, decay accelerating factor for complement (Cromer blood group))
CD55 antibody [N2C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CD55. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: K562 , THP-1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-CD55 Antikörper (ABIN2855732)

Kwon, Kim, Hwang, Kim, Kim, Kim, Lee, Im, Lee, Hwang: "Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genes." in: Transgenic research, Vol. 26, Issue 1, pp. 153-163, (2018) (PubMed).

Details zu CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Andere Bezeichnung: CD55 (CD55 Produkte)

Synonyme: CR antikoerper, CROM antikoerper, DAF antikoerper, TC antikoerper, Daf antikoerper, Daf-GPI antikoerper, Daf1 antikoerper, GPI-DAF antikoerper, CD55 molecule (Cromer blood group) antikoerper, CD55 molecule, decay accelerating factor for complement antikoerper, CD55 antikoerper, Cd55 antikoerper

Hintergrund: This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF), binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Cellular Localization: Isoform 1: Membrane , Isoform 2: Cell membrane , GPI-anchor

Molekulargewicht: 41 kDa

Gen-ID: 1604

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity