GOLGA5 Antikörper

Produktnummer ABIN2855796

Produktdetails anti-GOLGA5 Antikörper

Target: GOLGA5 (Golgin A5 (GOLGA5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GOLGA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Hamster, Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to GOLGA5 (golgin A5)
GOLGA5 antibody [N2C2], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GOLGA5. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Mouse brain , A549

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-GOLGA5 Antikörper (ABIN2855796)

Pérez-Rodriguez, de Jesús Ramírez-Lira, Wulff, Voldbor, Ramírez, Trujillo-Roldán, Valdez-Cruz: "Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis." in: PLoS ONE, Vol. 15, Issue 8, pp. e0237930, (2020) (PubMed).

Popa, Villeneuve, Stewart, Perez Garcia, Petrunkina Harrison, Moreau: "Genome-wide CRISPR screening identifies new regulators of glycoprotein secretion." in: Wellcome open research, Vol. 4, pp. 119, (2019) (PubMed).

Chang, Chen, Shen, Kung, Chuang, Chen: "Selective serotonin reuptake inhibitor, fluoxetine, impairs E-cadherin-mediated cell adhesion and alters calcium homeostasis in pancreatic beta cells." in: Scientific reports, Vol. 7, Issue 1, pp. 3515, (2019) (PubMed).

Reiling, Olive, Sanyal, Carette, Brummelkamp, Ploegh, Starnbach, Sabatini: "A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens." in: Nature cell biology, Vol. 15, Issue 12, pp. 1473-85, (2013) (PubMed).

Details zu GOLGA5

Target: GOLGA5 (Golgin A5 (GOLGA5))

Andere Bezeichnung: golgin A5 (GOLGA5 Produkte)

Synonyme: GOLIM5 antikoerper, RFG5 antikoerper, ret-II antikoerper, golim5 antikoerper, ret-ii antikoerper, rfg5 antikoerper, Ret-II antikoerper, im:7153094 antikoerper, sb:cb898 antikoerper, wu:fd50h11 antikoerper, zgc:66400 antikoerper, golgin A5 antikoerper, golgin A5 L homeolog antikoerper, golgi autoantigen, golgin subfamily a, 5 antikoerper, GOLGA5 antikoerper, golga5.L antikoerper, golga5 antikoerper, Golga5 antikoerper

Hintergrund: The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes a member of the golgin family of proteins, whose members localize to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues, the chimeric sequences have been designated RET-II and PTC5.

Cellular Localization: Golgi apparatus membrane, Single-pass type IV membrane protein

Molekulargewicht: 83 kDa

Gen-ID: 9950

UniProt: Q8TBA6