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Aurora A Antikörper (C-Term)

AURKA Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855868
  • Target Alle Aurora A (AURKA) Antikörper anzeigen
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Bindungsspezifität
    • 22
    • 11
    • 8
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 112
    • 67
    • 38
    • 21
    • 18
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 106
    • 18
    • 1
    Kaninchen
    Klonalität
    • 99
    • 25
    Polyklonal
    Konjugat
    • 76
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Aurora A Antikörper ist unkonjugiert
    Applikation
    • 90
    • 48
    • 32
    • 24
    • 14
    • 11
    • 9
    • 7
    • 7
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit Polyclonal antibody to Aurora A (aurora kinase A)
    Aurora A antibody [C3], C-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Aurora A. The exact sequence is proprietary.
    Isotyp
    IgG
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  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Validation: Overexpression

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.87 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Andere Bezeichnung
    aurora kinase A (AURKA Produkte)
    Hintergrund
    The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Centrosome , Spindle
    Molekulargewicht
    46 kDa
    Gen-ID
    6790
    UniProt
    O14965
    Pathways
    Zellzyklus, Asymmetric Protein Localization
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