SPHK1 Antikörper (C-Term)

Produktnummer ABIN2855922

Produktdetails anti-SPHK1 Antikörper

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPHK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to SPHK1 (sphingosine kinase 1)
SPHK1 antibody [C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SPHK1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Molt-4

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.17 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu SPHK1

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Andere Bezeichnung: sphingosine kinase 1 (SPHK1 Produkte)

Synonyme: CG1747 antikoerper, Dmel\\CG1747 antikoerper, SK1 antikoerper, Sphk1 antikoerper, SPHK1 antikoerper, F18E5.160 antikoerper, F18E5_160 antikoerper, sphingosine kinase 1 antikoerper, SPHK antikoerper, 1110006G24Rik antikoerper, Sk1 antikoerper, Spk1 antikoerper, Sphingosine kinase 1 antikoerper, sphingosine kinase 1 antikoerper, sphingosine kinase 1 L homeolog antikoerper, Sk1 antikoerper, SPHK1 antikoerper, sphk1.L antikoerper, Sphk1 antikoerper

Hintergrund: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM]

Molekulargewicht: 43 kDa

Gen-ID: 8877

UniProt: Q9NYA1

Pathways: VEGF Signaling