Adiponectin Receptor 1 Antikörper (C-Term)

Produktnummer ABIN2855945

Produktdetails anti-Adiponectin Receptor 1 Antikörper

Target: Adiponectin Receptor 1 (ADIPOR1)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adiponectin Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio)

Produktmerkmale: Rabbit Polyclonal antibody to Adiponectin Receptor 1 (adiponectin receptor 1)
Adiponectin Receptor 1 antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Adiponectin Receptor 1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Mouse white adipose tissue , rat muscle , mouse muscle

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-Adiponectin Receptor 1 Antikörper (ABIN2855945)

Ito, Higa, Goto, Aoshima, Ikuta, Ohashi, Yokoyama, Ohno, Egawa, Miyata, Goto: "Activation of adiponectin receptors has negative impact on muscle mass in C2C12 myotubes and fast-type mouse skeletal muscle." in: PLoS ONE, Vol. 13, Issue 10, pp. e0205645, (2019) (PubMed).

Details zu Adiponectin Receptor 1

Target: Adiponectin Receptor 1 (ADIPOR1)

Andere Bezeichnung: adiponectin receptor 1 (ADIPOR1 Produkte)

Hintergrund: The adiponectin receptors, ADIPOR1 and ADIPOR2 (MIM 607946), serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA, MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM]

Cellular Localization: Membrane

Molekulargewicht: 43 kDa

Gen-ID: 51094

UniProt: Q96A54

Pathways: AMPK Signaling