UGDH Antikörper
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- Target Alle UGDH Antikörper anzeigen
- UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UGDH Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
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Rabbit Polyclonal antibody to UGDH (UDP-glucose 6-dehydrogenase)
UGDH antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human UGDH. The exact sequence is proprietary.
- Isotyp
- IgG
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- Applikationshinweise
- WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: mouse liver , Rat liver , UGDH-transfected 293T
Validation: Orthogonal, Overexpression
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.36 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
- Andere Bezeichnung
- UDP-glucose 6-dehydrogenase (UGDH Produkte)
- Hintergrund
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The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia.
- Molekulargewicht
- 55 kDa
- Gen-ID
- 7358
- UniProt
- O60701
- Pathways
- Glycosaminoglycan Metabolic Process
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