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FDPS Antikörper

FDPS Reaktivität: Human WB, IHC (p), ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856081
  • Target Alle FDPS Antikörper anzeigen
    FDPS (Farnesyl Diphosphate Synthase (FDPS))
    Reaktivität
    • 50
    • 28
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 60
    • 7
    Kaninchen
    Klonalität
    • 61
    • 6
    Polyklonal
    Konjugat
    • 27
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FDPS Antikörper ist unkonjugiert
    Applikation
    • 39
    • 29
    • 14
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to FDPS (farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase))
    FDPS antibody [N1C3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human FDPS. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Mouse brain , rat liver

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.75 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    FDPS (Farnesyl Diphosphate Synthase (FDPS))
    Andere Bezeichnung
    farnesyl diphosphate synthase (FDPS Produkte)
    Synonyme
    CG12389 antikoerper, DmFPPS antikoerper, DmFPPSase antikoerper, DmFPS antikoerper, Dmel\\CG12389 antikoerper, FPS antikoerper, fpps antikoerper, fps antikoerper, l(2)k06103 antikoerper, v(2)k03514 antikoerper, NCU01175.1 antikoerper, 16.m00760 antikoerper, DDBDRAFT_0206220 antikoerper, DDBDRAFT_0215017 antikoerper, DDB_0206220 antikoerper, DDB_0215017 antikoerper, FPPS antikoerper, Ac2-125 antikoerper, (2E antikoerper, 6030492I17Rik antikoerper, AI256750 antikoerper, Fdpsl1 antikoerper, mKIAA1293 antikoerper, Farnesyl pyrophosphate synthase antikoerper, farnesyl diphosphate synthase antikoerper, farnesyl diphosphate synthase L homeolog antikoerper, farnesyl pyrophosphate synthase antikoerper, farnesyl pyrophosphate synthetase antikoerper, farnesyl-pyrophosphate synthetase antikoerper, FDP synthase antikoerper, Farnesyl pyrophosphate synthetase antikoerper, farnesyl diphosphate synthetase antikoerper, farnesyl pyrophosphate synthase 1 antikoerper, Fpps antikoerper, fdps antikoerper, fdps.L antikoerper, MGG_08649 antikoerper, TP03_0857 antikoerper, Tb09.160.4300 antikoerper, fpp antikoerper, BBOV_I000120 antikoerper, fps antikoerper, fpps antikoerper, FDPS antikoerper, Fdps antikoerper, fps1 antikoerper
    Hintergrund
    This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Cytoplasm
    Molekulargewicht
    48 kDa
    Gen-ID
    2224
    UniProt
    P14324
    Pathways
    Regulation of Muscle Cell Differentiation
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