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GSTa2 Antikörper

GSTa2 Reaktivität: Human WB, ICC, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856132
  • Target Alle GSTa2 Antikörper anzeigen
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Reaktivität
    • 38
    • 3
    • 1
    Human
    Wirt
    • 35
    • 4
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 18
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GSTa2 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 24
    • 18
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Spezifität
    This antibody was raised against human GSTA2 antibody. It is able to detect GSTA1, GSTA2, and GSTA3 proteins but not cross reacts with GSTA4 or GSTA5 proteins based on customer's feedback.
    Kreuzreaktivität
    Human, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to GSTA2 (glutathione S-transferase alpha 2)
    GSTA2 antibody [N1C3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human GSTA2. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product GSTa2 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: HepG2

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Andere Bezeichnung
    glutathione S-transferase alpha 2 (GSTa2 Produkte)
    Synonyme
    GSTA1 antikoerper, GST2 antikoerper, GSTA2-2 antikoerper, GTA2 antikoerper, GTH2 antikoerper, Gsta1 antikoerper, Gst2-2 antikoerper, Gstc-2 antikoerper, Gstc2 antikoerper, glutathione S-transferase alpha 2 antikoerper, glutathione S-transferase antikoerper, glutathione S-transferase, alpha 2 (Yc2) antikoerper, GSTA2 antikoerper, Gsta2 antikoerper
    Hintergrund
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

    Cellular Localization: Cytoplasm
    Molekulargewicht
    26 kDa
    Gen-ID
    2939
    UniProt
    P09210
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