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GLUD1 Antikörper

GLUD1 Reaktivität: Human WB, ELISA, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856181
  • Target Alle GLUD1 Antikörper anzeigen
    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
    Reaktivität
    • 36
    • 17
    • 16
    • 14
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 41
    • 9
    • 1
    Kaninchen
    Klonalität
    • 41
    • 10
    Polyklonal
    Konjugat
    • 29
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GLUD1 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 22
    • 19
    • 10
    • 10
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Drosophila melanogaster, Human, Maus, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to Glutamate Dehydrogenase (glutamate dehydrogenase 1)
    Glutamate Dehydrogenase antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Glutamate Dehydrogenase. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product GLUD1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: 293T , A431 , HeLa , HepG2

    Validation: Orthogonal

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.07 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Geiszler, Ugun-Klusek, Lawler, Pardon, Yuchun, Bai, Daykin, Auer, Bedford: "Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons." in: Scientific reports, Vol. 8, Issue 1, pp. 4833, (2019) (PubMed).

  • Target
    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
    Andere Bezeichnung
    glutamate dehydrogenase 1 (GLUD1 Produkte)
    Hintergrund
    L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate (Smith et al., 2001 [PubMed 11254391]). Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification (Mavrothalassitis et al., 1988 [PubMed 3368458]).[supplied by OMIM]

    Cellular Localization: Mitochondrion matrix
    Molekulargewicht
    61 kDa
    Gen-ID
    2746
    UniProt
    P00367
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Warburg Effekt
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