FOLR2 Antikörper

Produktnummer ABIN2856196

Produktdetails anti-FOLR2 Antikörper

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOLR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to Folate receptor beta (folate receptor 2 (fetal))
Folate receptor beta antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Folate Receptor beta. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.2 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-FOLR2 Antikörper (ABIN2856196)

Meredith, MacNeil, Trasler, Baltz: "Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size." in: Biology of reproduction, Vol. 94, Issue 6, pp. 125, (2017) (PubMed).

Details zu FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Andere Bezeichnung: folate receptor beta (FOLR2 Produkte)

Synonyme: FOLR2 antikoerper, BETA-HFR antikoerper, FBP antikoerper, FBP/PL-1 antikoerper, FR-BETA antikoerper, FR-P3 antikoerper, FBP2 antikoerper, Folbp-2 antikoerper, Folbp2 antikoerper, folate receptor 1 antikoerper, folate receptor beta antikoerper, folate receptor 2 (fetal) antikoerper, FOLR1 antikoerper, FOLR2 antikoerper, Folr2 antikoerper

Hintergrund: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

Cellular Localization: Cell membrane, Lipid-anchor , GPI-anchor , Secreted

Molekulargewicht: 29 kDa

Gen-ID: 2350

UniProt: P14207

Pathways: Dicarboxylic Acid Transport