PROC Antikörper
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- Target Alle PROC Antikörper anzeigen
- PROC (Vitamin K-dependent protein C (PROC))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PROC Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human
- Produktmerkmale
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Rabbit Polyclonal antibody to Protein C (vitamin K-dependent protein C)
Protein C antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Protein C. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product PROC Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Validation: Orthogonal
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- PROC (Vitamin K-dependent protein C (PROC))
- Andere Bezeichnung
- protein C, inactivator of coagulation factors Va and VIIIa (PROC Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
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The PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930, MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5, MIM 612309) and VIII (F8, see MIM 306700). Protein S (PROS1, MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM]
- Molekulargewicht
- 52 kDa
- Gen-ID
- 5624
- UniProt
- P04070
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