PANK1 Antikörper
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- Target Alle PANK1 Antikörper anzeigen
- PANK1 (Pantothenate Kinase 1 (PANK1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PANK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
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Rabbit Polyclonal antibody to PANK1 (pantothenate kinase 1)
PANK1 antibody [N3C3] - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human PANK1. The exact sequence is proprietary.
- Isotyp
- IgG
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- Applikationshinweise
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: Mouse liver , HepG2
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- PANK1 (Pantothenate Kinase 1 (PANK1))
- Andere Bezeichnung
- pantothenate kinase 1 (PANK1 Produkte)
- Hintergrund
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This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, have been identified.
Cellular Localization: Cytoplasm - Molekulargewicht
- 64 kDa
- Gen-ID
- 53354
- UniProt
- Q8TE04
- Pathways
- Ribonucleoside Biosynthetic Process
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