DCLK2 Antikörper

Produktnummer ABIN2856229

Produktdetails anti-DCLK2 Antikörper

Target: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCLK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to DCAMKL2 (doublecortin-like kinase 2)
DCAMKL2 antibody [N2C2], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DCAMKL2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A549 , H1299 , HCT116

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.16 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu DCLK2

Target: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Andere Bezeichnung: doublecortin like kinase 2 (DCLK2 Produkte)

Synonyme: CL2 antikoerper, CLICK-II antikoerper, CLICK2 antikoerper, CLIK2 antikoerper, DCAMKL2 antikoerper, DCDC3 antikoerper, DCDC3B antikoerper, DCK2 antikoerper, 6330415M09Rik antikoerper, AU044875 antikoerper, Click-II antikoerper, Dcamkl2 antikoerper, DCLK2 antikoerper, cb572 antikoerper, dclk antikoerper, sb:cb572 antikoerper, si:dkey-180n16.1 antikoerper, Dck2 antikoerper, RGD1308384 antikoerper, doublecortin like kinase 2 antikoerper, doublecortin-like kinase 2 antikoerper, doublecortin-like kinase 2a antikoerper, DCLK2 antikoerper, Dclk2 antikoerper, dclk2a antikoerper

Hintergrund: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

Molekulargewicht: 84 kDa

Gen-ID: 166614

UniProt: Q8N568