DPM1 Antikörper (Center)

Produktnummer ABIN2856272

Produktdetails anti-DPM1 Antikörper

Target: DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Rind (Kuh), Schwein, Ratte (Rattus), Xenopus laevis

Kreuzreaktivität (Details): Mouse (90 %), Bovine (92 %), Pig (93 %), Rat (91 %), Xenopus laevis (86 %)

Produktmerkmale: Rabbit Polyclonal antibody to DPM1 (dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit)
DPM1 antibody [N1C2]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DPM1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: NT2D1 , U87-MG , MCF-7

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.95 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu DPM1

Target: DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))

Andere Bezeichnung: DPM1 (DPM1 Produkte)

Synonyme: DPM1 antikoerper, zgc:101018 antikoerper, MGC114892 antikoerper, AI118379 antikoerper, AI194292 antikoerper, CDGIE antikoerper, MPDS antikoerper, DPMS antikoerper, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit antikoerper, dolichyl-phosphate mannosyltransferase subunit 1, catalytic antikoerper, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit S homeolog antikoerper, dolichol-phosphate (beta-D) mannosyltransferase 1 antikoerper, dpm1 antikoerper, DPM1 antikoerper, dpm1.S antikoerper, Dpm1 antikoerper

Hintergrund: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.

Cellular Localization: Endoplasmic reticulum

Molekulargewicht: 30 kDa

Gen-ID: 8813

Pathways: Inositol Metabolic Process