ENPP2 Antikörper (C-Term)

Produktnummer ABIN2856278

Produktdetails anti-ENPP2 Antikörper

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENPP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to Autotaxin (ectonucleotide pyrophosphatase/phosphodiesterase 2)
Autotaxin antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Autotaxin. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.13 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-ENPP2 Antikörper (ABIN2856278)

Tsukahara, Haniu, Uemura, Matsuda: "Porcine liver decomposition product-derived lysophospholipids promote microglial activation in vitro." in: Scientific reports, Vol. 10, Issue 1, pp. 3748, (2020) (PubMed).

Details zu ENPP2

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Andere Bezeichnung: ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2 Produkte)

Synonyme: ATX antikoerper, ATX-X antikoerper, AUTOTAXIN antikoerper, LysoPLD antikoerper, NPP2 antikoerper, PD-IALPHA antikoerper, PDNP2 antikoerper, Npps2 antikoerper, PD-Ialpha antikoerper, Pdnp2 antikoerper, MGC132047 antikoerper, atx antikoerper, zgc:63550 antikoerper, autotaxin antikoerper, enpp2 antikoerper, enpp2a antikoerper, enpp2b antikoerper, ectonucleotide pyrophosphatase/phosphodiesterase 2 antikoerper, ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog antikoerper, ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog antikoerper, ENPP2 antikoerper, Enpp2 antikoerper, enpp2 antikoerper, enpp2.L antikoerper, enpp2.S antikoerper

Hintergrund: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Cellular Localization: Secreted

Molekulargewicht: 99 kDa

Gen-ID: 5168

UniProt: Q13822