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ENPP2 Antikörper (C-Term)

ENPP2 Reaktivität: Human WB, FACS, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856278
  • Target Alle ENPP2 Antikörper anzeigen
    ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 56
    • 44
    • 14
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 71
    • 3
    • 1
    Kaninchen
    Klonalität
    • 73
    • 2
    Polyklonal
    Konjugat
    • 37
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ENPP2 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 24
    • 14
    • 14
    • 12
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit Polyclonal antibody to Autotaxin (ectonucleotide pyrophosphatase/phosphodiesterase 2)
    Autotaxin antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human Autotaxin. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Validation: Orthogonal

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.13 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Tsukahara, Haniu, Uemura, Matsuda: "Porcine liver decomposition product-derived lysophospholipids promote microglial activation in vitro." in: Scientific reports, Vol. 10, Issue 1, pp. 3748, (2020) (PubMed).

  • Target
    ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
    Andere Bezeichnung
    ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2 Produkte)
    Synonyme
    ATX antikoerper, ATX-X antikoerper, AUTOTAXIN antikoerper, LysoPLD antikoerper, NPP2 antikoerper, PD-IALPHA antikoerper, PDNP2 antikoerper, Npps2 antikoerper, PD-Ialpha antikoerper, Pdnp2 antikoerper, MGC132047 antikoerper, atx antikoerper, zgc:63550 antikoerper, autotaxin antikoerper, enpp2 antikoerper, enpp2a antikoerper, enpp2b antikoerper, ectonucleotide pyrophosphatase/phosphodiesterase 2 antikoerper, ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog antikoerper, ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog antikoerper, ENPP2 antikoerper, Enpp2 antikoerper, enpp2 antikoerper, enpp2.L antikoerper, enpp2.S antikoerper
    Hintergrund
    The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

    Cellular Localization: Secreted
    Molekulargewicht
    99 kDa
    Gen-ID
    5168
    UniProt
    Q13822
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