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DBNL Antikörper (N-Term)

DBNL Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856301
  • Target Alle DBNL Antikörper anzeigen
    DBNL (Drebrin-Like (DBNL))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 24
    • 19
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 36
    • 2
    • 1
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DBNL Antikörper ist unkonjugiert
    Applikation
    • 37
    • 18
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Maus, Ratte (Rattus), Rind (Kuh)
    Kreuzreaktivität (Details)
    Mouse (92 %), Rat (92 %), Bovine (84 %)
    Produktmerkmale
    Rabbit Polyclonal antibody to HIP55 (drebrin-like)
    HIP55 antibody [N1], N-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HIP55. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Kommentare

    Positive Control: HeLaS3 , Molt-4

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    DBNL (Drebrin-Like (DBNL))
    Andere Bezeichnung
    HIP55 (DBNL Produkte)
    Synonyme
    ABP1 antikoerper, HIP-55 antikoerper, HIP55 antikoerper, SH3P7 antikoerper, Abp1 antikoerper, mAbp1 antikoerper, Sh3p7 antikoerper, abp1 antikoerper, dbnl-B antikoerper, DBNL antikoerper, DKFZp459C0939 antikoerper, drebrin like antikoerper, drebrin-like antikoerper, drebrin like S homeolog antikoerper, drebrin 1 antikoerper, DBNL antikoerper, Dbnl antikoerper, dbnl.S antikoerper, LOC100148204 antikoerper, DBN1 antikoerper
    Hintergrund
    Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.

    Cellular Localization: Cytoplasm , cytoskeleton , Cell projection , lamellipodium
    Molekulargewicht
    48 kDa
    Gen-ID
    28988
    Pathways
    T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization
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