DBNL Antikörper (N-Term)
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- Target Alle DBNL Antikörper anzeigen
- DBNL (Drebrin-Like (DBNL))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DBNL Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Maus, Ratte (Rattus), Rind (Kuh)
- Kreuzreaktivität (Details)
- Mouse (92 %), Rat (92 %), Bovine (84 %)
- Produktmerkmale
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Rabbit Polyclonal antibody to HIP55 (drebrin-like)
HIP55 antibody [N1], N-term - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HIP55. The exact sequence is proprietary.
- Isotyp
- IgG
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- Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Kommentare
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Positive Control: HeLaS3 , Molt-4
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- DBNL (Drebrin-Like (DBNL))
- Andere Bezeichnung
- HIP55 (DBNL Produkte)
- Synonyme
- ABP1 antikoerper, HIP-55 antikoerper, HIP55 antikoerper, SH3P7 antikoerper, Abp1 antikoerper, mAbp1 antikoerper, Sh3p7 antikoerper, abp1 antikoerper, dbnl-B antikoerper, DBNL antikoerper, DKFZp459C0939 antikoerper, drebrin like antikoerper, drebrin-like antikoerper, drebrin like S homeolog antikoerper, drebrin 1 antikoerper, DBNL antikoerper, Dbnl antikoerper, dbnl.S antikoerper, LOC100148204 antikoerper, DBN1 antikoerper
- Hintergrund
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Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.
Cellular Localization: Cytoplasm , cytoskeleton , Cell projection , lamellipodium - Molekulargewicht
- 48 kDa
- Gen-ID
- 28988
- Pathways
- T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization
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