IRF8 Antikörper (C-Term)

Produktnummer ABIN2856323

Produktdetails anti-IRF8 Antikörper

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to IRF8 (interferon regulatory factor 8)
IRF8 antibody [C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IRF8. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: THP-1 nuclear extract

Validation: Comparison, Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu IRF8

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Andere Bezeichnung: interferon regulatory factor 8 (IRF8 Produkte)

Synonyme: zgc:92252 antikoerper, IRF8 antikoerper, MGC140338 antikoerper, DKFZp469B0320 antikoerper, H-ICSBP antikoerper, ICSBP antikoerper, ICSBP1 antikoerper, IRF-8 antikoerper, icsbp1 antikoerper, AI893568 antikoerper, Icsbp1 antikoerper, Myls antikoerper, interferon regulatory factor 8 antikoerper, interferon regulatory factor 8 L homeolog antikoerper, irf8 antikoerper, IRF8 antikoerper, irf8.L antikoerper, Irf8 antikoerper

Hintergrund: Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

Cellular Localization: Nucleus

Molekulargewicht: 48 kDa

Gen-ID: 3394

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin