CBX1 Antikörper (Center)

Produktnummer ABIN2856369

Produktdetails anti-CBX1 Antikörper

Target: CBX1 (Chromobox Homolog 1 (CBX1))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Rind (Kuh), Huhn, Schimpanse

Kreuzreaktivität (Details): Chicken (85 %), Chimpanzee (100 %), Bovine (100 %)

Produktmerkmale: Rabbit Polyclonal antibody to CBX1 / HP1 beta (chromobox homolog 1)
CBX1 / HP1 beta antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human CBX1 / HP1 beta. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CBX1

Target: CBX1 (Chromobox Homolog 1 (CBX1))

Andere Bezeichnung: CBX1 / HP1 beta (CBX1 Produkte)

Synonyme: CBX antikoerper, HP1-BETA antikoerper, HP1Hs-beta antikoerper, HP1Hsbeta antikoerper, M31 antikoerper, MOD1 antikoerper, p25beta antikoerper, Cbx antikoerper, Cbx-rs2 antikoerper, E430007M08Rik antikoerper, HP1B antikoerper, Hp1beta antikoerper, cbx1 antikoerper, wu:fe14b09 antikoerper, zgc:55739 antikoerper, zgc:86924 antikoerper, chromobox 1 antikoerper, chromobox homolog 1a (HP1 beta homolog Drosophila) antikoerper, chromobox 1 S homeolog antikoerper, chromobox homolog 1b (HP1 beta homolog Drosophila) antikoerper, CBX1 antikoerper, Cbx1 antikoerper, cbx1a antikoerper, cbx1.S antikoerper, cbx1b antikoerper

Hintergrund: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Cellular Localization: Nucleus

Molekulargewicht: 21 kDa

Gen-ID: 10951