DPY19L4 Antikörper (C-Term)

Produktnummer ABIN2856454

Produktdetails anti-DPY19L4 Antikörper

Target: DPY19L4 (Dpy-19-Like 4 (DPY19L4))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPY19L4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Mouse (94 %)

Produktmerkmale: Rabbit Polyclonal antibody to DPY19L4 (dpy-19-like 4 (C. elegans))
DPY19L4 antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human DPY19L4. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: A549 , HeLa , HepG2 , HCT116

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu DPY19L4

Target: DPY19L4 (Dpy-19-Like 4 (DPY19L4))

Andere Bezeichnung: DPY19L4 (DPY19L4 Produkte)

Synonyme: Gm1023 antikoerper, Narg3 antikoerper, RGD1305828 antikoerper, dpy-19 like 4 antikoerper, dpy-19-like 4 (C. elegans) antikoerper, DPY19L4 antikoerper, Dpy19l4 antikoerper

Hintergrund: Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Cellular Localization: Membrane

Molekulargewicht: 84 kDa

Gen-ID: 286148