SPOP-B Antikörper (Center)

Produktnummer ABIN2856462

Produktdetails anti-SPOP-B Antikörper

Target: SPOP-B (Speckle-Type POZ Protein (SPOP-B))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPOP-B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität: Ratte (Rattus), Xenopus tropicalis, Rhesusaffen, Rind (Kuh)

Kreuzreaktivität (Details): Rat (100 %), Xenopus Tropicalis (100 %), Rhesus Monkey (100 %), Bovine (100 %)

Produktmerkmale: Rabbit Polyclonal antibody to SPOP (speckle-type POZ protein)
SPOP antibody [N1C1]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SPOP. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Immunohistochemistry Assay-dependent dilution Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunohistochemistryAssay-dependent dilution Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , Raji , mouse brain

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu SPOP-B

Target: SPOP-B (Speckle-Type POZ Protein (SPOP-B))

Andere Bezeichnung: SPOP (SPOP-B Produkte)

Synonyme: BTBD32 antikoerper, TEF2 antikoerper, AI315626 antikoerper, Pcif1 antikoerper, zgc:64140 antikoerper, spop antikoerper, tef2 antikoerper, speckle type BTB/POZ protein antikoerper, speckle-type POZ protein antikoerper, speckle type POZ protein S homeolog antikoerper, SPOP antikoerper, Spop antikoerper, spop antikoerper, spop.S antikoerper

Hintergrund: This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.

Cellular Localization: Nucleus

Molekulargewicht: 42 kDa

Gen-ID: 8405