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DENND1B Antikörper (Center)

DENND1B Reaktivität: Human, Maus WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856495
  • Target Alle DENND1B Antikörper anzeigen
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 31
    • 19
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 45
    • 1
    Kaninchen
    Klonalität
    • 46
    Polyklonal
    Konjugat
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DENND1B Antikörper ist unkonjugiert
    Applikation
    • 39
    • 16
    • 15
    • 14
    • 13
    • 13
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Produktmerkmale
    Rabbit Polyclonal antibody to DENND1B (DENN/MADD domain containing 1B)
    DENND1B antibody [N1C1]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human DENND1B. The exact sequence is proprietary.
    Isotyp
    IgG
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    Discover our top product DENND1B Primärantikörper
  • Applikationshinweise
    Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
    Kommentare

    Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.9 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Andere Bezeichnung
    DENND1B (DENND1B Produkte)
    Synonyme
    C1ORF18 antikoerper, C1orf218 antikoerper, FAM31B antikoerper, 4632404N19Rik antikoerper, 4930467M19Rik antikoerper, 6820401H01Rik antikoerper, F730008N07Rik antikoerper, Fam31b antikoerper, si:ch211-195i21.1 antikoerper, DENN domain containing 1B antikoerper, DENN/MADD domain containing 1B antikoerper, DENND1B antikoerper, dennd1b antikoerper, Dennd1b antikoerper
    Hintergrund
    Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM]

    Molekulargewicht
    48 kDa
    Gen-ID
    163486
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