DYRK3 Antikörper

Produktnummer ABIN2856542

Produktdetails anti-DYRK3 Antikörper

Target: DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYRK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to Dyrk3 (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3)
Dyrk3 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Dyrk3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.68 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu DYRK3

Target: DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

Andere Bezeichnung: dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3 Produkte)

Synonyme: DYRK5 antikoerper, RED antikoerper, REDK antikoerper, hYAK3-2 antikoerper, BC006704 antikoerper, DYRK3 antikoerper, MGC89944 antikoerper, dual specificity tyrosine phosphorylation regulated kinase 3 antikoerper, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 antikoerper, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3 antikoerper, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3 L homeolog antikoerper, DYRK3 antikoerper, Dyrk3 antikoerper, dyrk3 antikoerper, dyrk3.L antikoerper

Hintergrund: This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.

Cellular Localization: Nucleus

Molekulargewicht: 66 kDa

Gen-ID: 8444

UniProt: O43781

Pathways: Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha