Nemo-Like Kinase Antikörper
-
- Target Alle Nemo-Like Kinase (NLK) Antikörper anzeigen
- Nemo-Like Kinase (NLK)
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Nemo-Like Kinase Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
-
Rabbit Polyclonal antibody to NLK (nemo-like kinase)
NLK antibody [N3C3] - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human NLK. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product NLK Primärantikörper
-
anti-Nemo-Like Kinase (NLK) (AA 416-515) antibody
NLK Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 2B11 unconjugated
anti-Nemo-Like Kinase (NLK) (AA 275-300) antibodyNLK Reaktivität: Human WB, IF, FACS Wirt: Kaninchen Polyclonal RB16621 unconjugated
anti-Nemo-Like Kinase (NLK) (AA 408-436), (C-Term) antibodyNLK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB34651 unconjugated
anti-Nemo-Like Kinase (NLK) antibodyNLK Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Nemo-Like Kinase (NLK) (AA 278-527) antibodyNLK Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (AA 278-527) antibodyNLK Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (AA 406-436), (C-Term) antibodyNLK Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB3358 unconjugated
anti-Nemo-Like Kinase (NLK) (AA 1-515) antibodyNLK Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (N-Term) antibodyNLK Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (Thr286) antibodyNLK Reaktivität: Human WB, FACS, IF/ICC Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
-
Positive Control: Mouse brain , HeLa , NLK-transfected 293T
Validation: Overexpression
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- Target
- Nemo-Like Kinase (NLK)
- Andere Bezeichnung
- nemo like kinase (NLK Produkte)
- Hintergrund
-
Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP (By similarity). Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
Cellular Localization: Nucleus (By similarity) , Cytoplasm (By similarity) - Molekulargewicht
- 58 kDa
- Gen-ID
- 51701
- UniProt
- Q9UBE8
- Pathways
- Ubiquitin Proteasome Pathway
-
