TIMM17A Antikörper (C-Term)

Produktnummer ABIN2856587

Produktdetails anti-TIMM17A Antikörper

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMM17A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit polyclonal antibody to Tim17 (translocase of inner mitochondrial membrane 17 homolog A (yeast))
TIM17 antibody [C1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TIM17. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HeLa

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-TIMM17A Antikörper (ABIN2856587)

Sprenger, Wani, Hesseling, König, Patron, MacVicar, Ahola, Wai, Barth, Rugarli, Bergami, Langer: "Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy." in: EMBO molecular medicine, Vol. 11, Issue 1, (2019) (PubMed).

Details zu TIMM17A

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Andere Bezeichnung: translocase of inner mitochondrial membrane 17A (TIMM17A Produkte)

Synonyme: TIM17 antikoerper, TIM17A antikoerper, Tim17 antikoerper, Timm17 antikoerper, 17kDa antikoerper, mTim17a antikoerper, translocase of inner mitochondrial membrane 17A antikoerper, translocase of inner mitochondrial membrane 17a antikoerper, TIMM17A antikoerper, Timm17a antikoerper

Hintergrund: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

Cellular Localization: Mitochondrion inner membrane, Multi-pass membrane protein

Molekulargewicht: 18 kDa

Gen-ID: 10440

UniProt: Q99595