TIMM17A Antikörper (C-Term)

Produktnummer ABIN2856587

Produktdetails anti-TIMM17A Antikörper

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMM17A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit polyclonal antibody to Tim17 (translocase of inner mitochondrial membrane 17 homolog A (yeast))
TIM17 antibody [C1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TIM17. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HeLa

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-TIMM17A Antikörper (ABIN2856587)

Sprenger, Wani, Hesseling, König, Patron, MacVicar, Ahola, Wai, Barth, Rugarli, Bergami, Langer: "Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy." in: EMBO molecular medicine, Vol. 11, Issue 1, (2019) (PubMed).

Details zu TIMM17A

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Andere Bezeichnung: translocase of inner mitochondrial membrane 17A (TIMM17A Produkte)

Hintergrund: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

Cellular Localization: Mitochondrion inner membrane, Multi-pass membrane protein

Molekulargewicht: 18 kDa

Gen-ID: 10440

UniProt: Q99595