INHBA Antikörper (C-Term)

Produktnummer ABIN2856600

Produktdetails anti-INHBA Antikörper

Target: INHBA (Inhibin, beta A (INHBA))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INHBA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to Inhibin beta A (inhibin, beta A)
Inhibin beta A antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Inhibin beta A. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.66 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu INHBA

Target: INHBA (Inhibin, beta A (INHBA))

Andere Bezeichnung: inhibin subunit beta A (INHBA Produkte)

Synonyme: EDF antikoerper, FRP antikoerper, actba antikoerper, inhba antikoerper, inhbaa-001 antikoerper, edf antikoerper, frp antikoerper, INHB antikoerper, inhbal antikoerper, zgc:158348 antikoerper, inhibin beta A subunit antikoerper, inhibin beta-A antikoerper, inhibin, beta Aa antikoerper, inhibin beta A antikoerper, inhibin, beta Ab antikoerper, INHBA antikoerper, Inhba antikoerper, inhbaa antikoerper, inhba antikoerper, inhbab antikoerper

Hintergrund: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Cellular Localization: Secreted

Molekulargewicht: 47 kDa

Gen-ID: 3624

UniProt: P08476

Pathways: Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagie