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TJP1 Antikörper (N-Term)

KO Validated TJP1 Reaktivität: Human WB, IP, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856624
  • Target Alle TJP1 Antikörper anzeigen
    TJP1 (Tight Junction Protein 1 (TJP1))
    Bindungsspezifität
    • 16
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 66
    • 44
    • 37
    • 20
    • 18
    • 9
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 61
    • 3
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 63
    • 6
    Polyklonal
    Konjugat
    • 39
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TJP1 Antikörper ist unkonjugiert
    Applikation
    • 52
    • 20
    • 18
    • 15
    • 14
    • 13
    • 12
    • 11
    • 10
    • 8
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit Polyclonal antibody to ZO-1 (tight junction protein 1 (zona occludens 1))
    ZO-1 antibody [N1N2], N-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the N-terminus region of human ZO-1. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product TJP1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: HeLa

    Validation: KO/KD

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.22 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Zhang, Heruth, Wu, Zhang, Nsumu, Shortt, Li, Jiang, Wang, Friesen, Li, Ye: "Functional characterization of SLC26A3 c.392C>G (p.P131R) mutation in intestinal barrier function using CRISPR/CAS9-created cell models." in: Cell & bioscience, Vol. 9, pp. 40, (2019) (PubMed).

  • Target
    TJP1 (Tight Junction Protein 1 (TJP1))
    Andere Bezeichnung
    tight junction protein 1 (TJP1 Produkte)
    Synonyme
    ZO-1 antikoerper, ZO1 antikoerper, zo1 antikoerper, tight junction protein 1 antikoerper, tight junction protein ZO-1 antikoerper, TJP1 antikoerper, Tjp1 antikoerper, LOC396567 antikoerper
    Hintergrund
    This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.

    Cellular Localization: Cell membrane, Peripheral membrane protein, Cytoplasmic side , Cell junction , tight junction
    Molekulargewicht
    195 kDa
    Gen-ID
    7082
    UniProt
    Q07157
    Pathways
    Carbohydrate Homeostasis, Cell-Cell Junction Organization
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