PSMC3 Antikörper

Produktnummer ABIN2856692

Produktdetails anti-PSMC3 Antikörper

Target: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Whole Mount) (IHC (wm))

Kreuzreaktivität: Human, Zebrafisch (Danio rerio)

Produktmerkmale: Rabbit polyclonal antibody to PSMC3 (proteasome (prosome, macropain) 26S subunit, ATPase, 3)
PSMC3 antibody [N1C2]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PSMC3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Molt-4

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PSMC3

Target: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Andere Bezeichnung: proteasome 26S subunit, ATPase 3 (PSMC3 Produkte)

Synonyme: TBP1 antikoerper, TBP-1 antikoerper, wu:fb39a02 antikoerper, zgc:86713 antikoerper, psmc3 antikoerper, MGC89608 antikoerper, PSMC3 antikoerper, NV15940 antikoerper, 23.m06430 antikoerper, DDBDRAFT_0186002 antikoerper, DDBDRAFT_0232967 antikoerper, DDB_0186002 antikoerper, DDB_0232967 antikoerper, psmc3-b antikoerper, tbp10 antikoerper, psmc3-a antikoerper, proteasome 26S subunit, ATPase 3 antikoerper, proteasome (prosome, macropain) 26S subunit, ATPase 3 antikoerper, 26S protease regulatory subunit 6A antikoerper, 26S protease regulatory subunit 6a antikoerper, 26S protease regulatory subunit 6A-B antikoerper, 26S protease regulatory subunit 6A, putative antikoerper, proteasome 26S subunit, ATPase 3 S homeolog antikoerper, nth-like DNA glycosylase 1 S homeolog antikoerper, PSMC3 antikoerper, Psmc3 antikoerper, HCAG_00069 antikoerper, GL50803_4365 antikoerper, EDI_316920 antikoerper, CpipJ_CPIJ006888 antikoerper, CpipJ_CPIJ006889 antikoerper, CpipJ_CPIJ010864 antikoerper, prs6a antikoerper, psmc3 antikoerper, LOC100115023 antikoerper, BBOV_IV004580 antikoerper, CGB_M2140W antikoerper, psmC3 antikoerper, LOC100637883 antikoerper, psmc3.S antikoerper, nthl1.S antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.

Cellular Localization: Cytoplasm (Potential) , Nucleus

Molekulargewicht: 49 kDa

Gen-ID: 5702

UniProt: P17980

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway