OFD1 Antikörper (Center)

Produktnummer ABIN2856726

Produktdetails anti-OFD1 Antikörper

Target: OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OFD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktmerkmale: Rabbit Polyclonal antibody to OFD1 (oral-facial-digital syndrome 1)
OFD1 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human OFD1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*

Kommentare:

Positive Control: Molt-4

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.96 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-OFD1 Antikörper (ABIN2856726)

Zhang, Li, Siu, Luo, Yu: "Distinct Roles of TRAPPC8 and TRAPPC12 in Ciliogenesis via Their Interactions With OFD1." in: Frontiers in cell and developmental biology, Vol. 8, pp. 148, (2020) (PubMed).

Details zu OFD1

Target: OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))

Andere Bezeichnung: OFD1 (OFD1 Produkte)

Synonyme: 71-7A antikoerper, CXorf5 antikoerper, JBTS10 antikoerper, RP23 antikoerper, SGBS2 antikoerper, RGD1562231 antikoerper, OFD1, centriole and centriolar satellite protein antikoerper, OFD1 antikoerper, ofd1 antikoerper, Ofd1 antikoerper

Hintergrund: This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified, a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. Alternatively spliced transcripts have been described for this gene but the biological validity of these transcripts has not been determined.

Cellular Localization: Cytoplasm , Centrosome

Molekulargewicht: 117 kDa

Gen-ID: 8481

Pathways: M Phase