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OFD1 Antikörper (Center)

OFD1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856726
  • Target Alle OFD1 Antikörper anzeigen
    OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))
    Bindungsspezifität
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 12
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 12
    Kaninchen
    Klonalität
    • 12
    Polyklonal
    Konjugat
    • 8
    • 2
    • 1
    • 1
    Dieser OFD1 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Produktmerkmale
    Rabbit Polyclonal antibody to OFD1 (oral-facial-digital syndrome 1)
    OFD1 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human OFD1. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*
    Kommentare

    Positive Control: Molt-4

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.96 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Zhang, Li, Siu, Luo, Yu: "Distinct Roles of TRAPPC8 and TRAPPC12 in Ciliogenesis via Their Interactions With OFD1." in: Frontiers in cell and developmental biology, Vol. 8, pp. 148, (2020) (PubMed).

  • Target
    OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))
    Andere Bezeichnung
    OFD1 (OFD1 Produkte)
    Synonyme
    71-7A antikoerper, CXorf5 antikoerper, JBTS10 antikoerper, RP23 antikoerper, SGBS2 antikoerper, RGD1562231 antikoerper, OFD1, centriole and centriolar satellite protein antikoerper, OFD1 antikoerper, ofd1 antikoerper, Ofd1 antikoerper
    Hintergrund
    This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified, a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. Alternatively spliced transcripts have been described for this gene but the biological validity of these transcripts has not been determined.

    Cellular Localization: Cytoplasm , Centrosome
    Molekulargewicht
    117 kDa
    Gen-ID
    8481
    Pathways
    M Phase
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