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FIG4 Antikörper (Center)

FIG4 Reaktivität: Human WB, IHC (p), ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856730
  • Target Alle FIG4 Antikörper anzeigen
    FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Center
    Reaktivität
    • 28
    • 16
    • 15
    • 1
    Human
    Wirt
    • 43
    • 1
    Kaninchen
    Klonalität
    • 43
    • 1
    Polyklonal
    Konjugat
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FIG4 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 17
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Kreuzreaktivität
    Schimpanse
    Kreuzreaktivität (Details)
    Chimpanzee (100 %)
    Produktmerkmale
    Rabbit Polyclonal antibody to FIG4 (FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae))
    FIG4 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human FIG4. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Kommentare

    Positive Control: HeLa , HCT116

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
    Andere Bezeichnung
    FIG4 (FIG4 Produkte)
    Synonyme
    A530089I17Rik antikoerper, AI326867 antikoerper, Sac3 antikoerper, ALS11 antikoerper, CMT4J antikoerper, KIAA0274 antikoerper, SAC3 antikoerper, YVS antikoerper, dJ249I4.1 antikoerper, Kiaa0274 antikoerper, RGD1311375 antikoerper, FIG4 phosphoinositide 5-phosphatase antikoerper, Fig4 antikoerper, FIG4 antikoerper
    Hintergrund
    The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.

    Cellular Localization: Endosome membrane
    Molekulargewicht
    104 kDa
    Gen-ID
    9896
    Pathways
    Inositol Metabolic Process
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