alpha 2 Antiplasmin Antikörper (Center)

Produktnummer ABIN2856732

Produktdetails anti-alpha 2 Antiplasmin Antikörper

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha 2 Antiplasmin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Kaninchen, Rind (Kuh)

Kreuzreaktivität (Details): Rabbit (86 %), Bovine (83 %)

Produktmerkmale: Rabbit Polyclonal antibody to alpha 2 Antiplasmin (serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2)
alpha 2 Antiplasmin antibody [N3C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human alpha 2 Antiplasmin. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse liver

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu alpha 2 Antiplasmin

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Andere Bezeichnung: alpha 2 Antiplasmin (SERPINF2 Produkte)

Synonyme: A2AP antikoerper, AAP antikoerper, ALPHA-2-PI antikoerper, API antikoerper, PLI antikoerper, serpin antikoerper, AI747498 antikoerper, Pli antikoerper, Serpimf2 antikoerper, serpinf2 antikoerper, serpinf2l antikoerper, wu:fd57d08 antikoerper, Dmrs91 antikoerper, Pedf antikoerper, serpin family F member 2 antikoerper, serpin family F member 1 antikoerper, serine (or cysteine) peptidase inhibitor, clade F, member 2 antikoerper, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a antikoerper, SERPINF2 antikoerper, Serpinf2 antikoerper, SERPINF1 antikoerper, serpinf2a antikoerper, Serpinf1 antikoerper

Hintergrund: This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Secreted

Molekulargewicht: 55 kDa

Gen-ID: 5345

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones