GCM2 Antikörper (Center)

Produktnummer ABIN2856796

Produktdetails anti-GCM2 Antikörper

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Rabbit polyclonal antibody to GCM2 (glial cells missing homolog 2 (Drosophila))
GCM2 antibody [N3C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GCM2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: A431

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.75 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu GCM2

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Andere Bezeichnung: GCM2 (GCM2 Produkte)

Synonyme: GCMb antikoerper, Gcm-2 antikoerper, gcm-2 antikoerper, GCMB antikoerper, hGCMb antikoerper, Gcm-rs1 antikoerper, Gcm1 antikoerper, Gcm1-rs2 antikoerper, glial cells missing homolog 2 antikoerper, glial cells missing homolog 2 (Drosophila) antikoerper, glial cells missing homolog 2 S homeolog antikoerper, GCM2 antikoerper, gcm2 antikoerper, gcm2.S antikoerper, Gcm2 antikoerper

Hintergrund: This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism.

Cellular Localization: Nucleus

Molekulargewicht: 57 kDa

Gen-ID: 9247