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BCL2L10 Antikörper

BCL2L10 Reaktivität: Human WB, ICC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856828
  • Target Alle BCL2L10 Antikörper anzeigen
    BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
    Reaktivität
    • 20
    • 16
    • 15
    Human
    Wirt
    • 31
    • 4
    Kaninchen
    Klonalität
    • 32
    • 3
    Polyklonal
    Konjugat
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BCL2L10 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 13
    • 13
    • 10
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit polyclonal antibody to BCL2L10 (BCL2-like 10 (apoptosis facilitator))
    BCL2L10 antibody [N2C2], Internal
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L10. The exact sequence is proprietary.
    Isotyp
    IgG
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    Discover our top product BCL2L10 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.32 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
    Andere Bezeichnung
    BCL2 like 10 (BCL2L10 Produkte)
    Synonyme
    BCL-B antikoerper, Boo antikoerper, Diva antikoerper, AA420380 antikoerper, AU023065 antikoerper, C85687 antikoerper, NR-13 antikoerper, mcl1l antikoerper, nr13 antikoerper, sb:cb78 antikoerper, BCL2 like 10 antikoerper, Bcl2-like 10 antikoerper, BCL2-like 10 (apoptosis facilitator) antikoerper, BCL2L10 antikoerper, Bcl2l10 antikoerper, bcl2l10 antikoerper
    Hintergrund
    The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

    Cellular Localization: Mitochondrion , Nucleus membrane
    Molekulargewicht
    22 kDa
    Gen-ID
    10017
    UniProt
    Q9HD36
    Pathways
    Positive Regulation of Endopeptidase Activity
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