DEDD Antikörper

Produktnummer ABIN2856831

Produktdetails anti-DEDD Antikörper

Target: DEDD (Death Effector Domain Containing (DEDD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEDD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to DEDD (death effector domain containing)
DEDD antibody [N3C2], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human DEDD. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: mouse leukocyte treated with CFA

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.42 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu DEDD

Target: DEDD (Death Effector Domain Containing (DEDD))

Andere Bezeichnung: death effector domain containing (DEDD Produkte)

Synonyme: CASP8IP1 antikoerper, DEDD1 antikoerper, DEFT antikoerper, FLDED1 antikoerper, Dedpro1 antikoerper, KE05 antikoerper, Deft antikoerper, death effector domain containing antikoerper, death effector domain-containing antikoerper, DEDD antikoerper, Dedd antikoerper

Hintergrund: This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Cellular Localization: Cytoplasm , Nucleus , nucleolus

Molekulargewicht: 37 kDa

Gen-ID: 9191

UniProt: O75618