ALDH1A1 Antikörper (C-Term)
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- Target Alle ALDH1A1 Antikörper anzeigen
- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ALDH1A1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
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Rabbit Polyclonal antibody to ALDH1A1 (aldehyde dehydrogenase 1 family, member A1)
ALDH1A1 antibody [C3], C-term - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ALDH1A1. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product ALDH1A1 Primärantikörper
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- Applikationshinweise
- WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: A549 , mouse liver
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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ALDH1A3 affects colon cancer in vitro proliferation and invasion depending on CXCR4 status." in: British journal of cancer, Vol. 118, Issue 2, pp. 224-232, (2019) (PubMed).
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ALDH1A3 affects colon cancer in vitro proliferation and invasion depending on CXCR4 status." in: British journal of cancer, Vol. 118, Issue 2, pp. 224-232, (2019) (PubMed).
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- Target
- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
- Andere Bezeichnung
- aldehyde dehydrogenase 1 family member A1 (ALDH1A1 Produkte)
- Hintergrund
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This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.
Cellular Localization: Cytoplasm - Molekulargewicht
- 55 kDa
- Gen-ID
- 216
- UniProt
- P00352
- Pathways
- Dopaminergic Neurogenesis
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