ERCC8 Antikörper (Center)
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- Target Alle ERCC8 Antikörper anzeigen
- ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))
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Bindungsspezifität
- Center
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ERCC8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Produktmerkmale
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Rabbit Polyclonal antibody to ERCC8 (excision repair cross-complementing rodent repair deficiency, complementation group 8)
ERCC8 antibody - Aufreinigung
- Affinity purified by Protein A.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human ERCC8. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product ERCC8 Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
- Kommentare
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Positive Control: Molt-4 , C8D30 , Rat2
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 5.39 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))
- Andere Bezeichnung
- ERCC8 (ERCC8 Produkte)
- Synonyme
- zgc:103550 antikoerper, CKN1 antikoerper, CSA antikoerper, UVSS2 antikoerper, Ckn1 antikoerper, 2410022P04Rik antikoerper, 2810431L23Rik antikoerper, 4631412O06Rik antikoerper, B130065P18Rik antikoerper, Csa antikoerper, excision repair cross-complementation group 8 antikoerper, ERCC excision repair 8, CSA ubiquitin ligase complex subunit antikoerper, excision repaiross-complementing rodent repair deficiency, complementation group 8 antikoerper, ercc8 antikoerper, ERCC8 antikoerper, Ercc8 antikoerper
- Hintergrund
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This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
Cellular Localization: Nucleus - Molekulargewicht
- 44 kDa
- Gen-ID
- 1161
- Pathways
- DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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