8-OHDG
EIA, IHC (fro), IF
Wirt: Maus
Monoclonal
15A3
unconjugated
Applikationshinweise
ELISA: >1:250,000, IHC-P: >1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
Supplied as liquid whole serum without preservative
Konservierungsmittel
Without preservative
Handhabung
Avoid repeated freeze/thaw cycles
Lagerung
-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Tuerdi, Kikuta, Kinoshita, Kamogashira, Kondo, Yamasoba: "Zone-specific damage of the olfactory epithelium under protein restriction." in: Scientific reports, Vol. 10, Issue 1, pp. 22175, (2021) (PubMed).
Jeannot, Pogribny, Beland, Rusyn: "Chronic administration of ethanol leads to an increased incidence of hepatocellular adenoma by promoting H-ras-mutated cells." in: Cancer letters, Vol. 301, Issue 2, pp. 161-7, (2011) (PubMed).
8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually leads to several diseases in humans, such as arteriosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer?s disease.